One of our most favorite makers (and we certainly don't like to play favorites) is Brooklyn-based Industry City Distillery.
Five friends founded City Foundry as “a research and design group focused on improving small-scale manufacturing processes through the blending of science and art”. Then, they put all that technical know-how to work making vodka.
Industry City was their first long-term project. They designed, engineered and built all of their equipment in-house with an eye to innovation. They proudly proclaim that “a distillery is equal parts biology, chemistry, physics, and engineering; Industry Standard is the tasty application of our collective curiosities and interests.”